MITOCHONDRIAL MEDICINE

Within the Mitochondrial Medicine Group fundamentally-oriented and applied studies that range “from molecule to man” are carried out under the guidance of scientist with a clinical, (cell)biological or (bio)chemical background.

The information gathered is used for the development of new treatment modalities for diseases and adverse-health conditions in which the mitochondrial energy capacity is decreased. Defects of the oxidative phosphorylation system in man are amongst the most frequently encountered inborn errors of metabolism and the study of patients with these devastating disorders has revealed important information about the role that mitochondria play in the normal process of ageing in e.g. neurodegenerative disease like Parkinson disease.

Theme leader:  Prof. Dr. Jan Smeitink
Coordinators: Dr. Leo Nijtmans and Dr. Peter Willems
URL: www.ncmd.nl , www.csb-bioenergetics.nl, www.khondrion.nl

Staffmembers and Postdoctoral fellows: Dr. Mirian Janssen, Prof. Dr. Martijn Huijnen, Prof. Dr. Arend Heerschap, Prof. Dr. Be Wieringa, Dr. Jack Fransen, Dr. Bert van de Heuvel, Dr. Eva Morava, Drs. Maaike de Vries, Dr. Ir. Rutger Vogel, Dr. Merei Huigsloot, Dr. John Esseling, Dr. Richard Rodenburg, Dr. Werner Koopman, Dr. Peggy Roestenberg, Prof. Dr. Martin Lammens, Dr. Bas Wanschers, Dr. Urszula Kudla, Dr. Jacques Driessen, Dr. Antoon Janssen, Dr. Ad de Groof, Dr. Marinette van der Graaf, Dr. Mina Pellegrini, Dr. Lucia Valente, Prof. dr. Hans Spelbrink, Dr. Cindy Dieteren

PhD students: Drs.Maria Antonietta Calvaruso, Drs. Murtada Farhoud, Drs. Saskia Hoefs, Drs. An Jonckheere, Drs. Fimmie Reinecke, Drs. Paulien Smits, Drs. Federica Valsecchi, Ing. Hans Wessels, Drs. Jessica Nouws, Drs. Saskia Wortmann, Ir. Kim van der Ven, Drs. Ganesh Manjeri, Drs. Saskia Koene, Drs. Marleen Forkink.

Technicians: Mariel van den Brand, Herman Swarts, Sjenet van Emst-de Vries, Roel Smeets, Sjaak van Asten, Jitske Jansen.